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Mitochondrial Inhibitors and Neurodegenerative Disorders
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ISBN: 9780896038059

Mitochondria have long been the Rodney Dangerfield of cellular organelles. Believed to be the remnants of bacterial infection of eukaryotic cells eons ago, the mitochondrion evolved a sym… Más…

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Mitochondrial Inhibitors and Neurodegenerative Disorders
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Mitochondrial Inhibitors and Neurodegenerative Disorders - libro nuevo

ISBN: 9780896038059

Mitochondria have long been the Rodney Dangerfield of cellular organelles. Believed to be the remnants of bacterial infection of eukaryotic cells eons ago, the mitochondrion evolved a sym… Más…

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Mitochondrial Inhibitors and Neurodegenerative Disorders - Sanberg, Paul R. Nishino, Hitoo Borlongan, Cesario V.
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Sanberg, Paul R. Nishino, Hitoo Borlongan, Cesario V.:
Mitochondrial Inhibitors and Neurodegenerative Disorders - Primera edición

1999

ISBN: 9780896038059

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Paul R. Sanberg:
Mitochondrial Inhibitors and Neurodegenerative Disorders Contemporary Neuroscience - Pasta blanda

2010, ISBN: 9780896038059

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Paul R. Sanberg:
Mitochondrial Inhibitors and Neurodegenerative Disorders Contemporary Neuroscience - Pasta blanda

2010, ISBN: 9780896038059

Softcover, PLEASE NOTE, WE DO NOT SHIP TO DENMARK. New Book. Shipped from US in 4 to 14 days. Established seller since 2000. Please note we cannot offer an expedited shipping service from… Más…

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Detalles del libro
Mitochondrial Inhibitors and Neurodegenerative Disorders

Respected investigators from around the world critically review what is known about the role of mitochondrial inhibitors in cell death and the onset of neurodegeneration. These distinguished researchers -- many pioneers in the field -- detail the symptomology, origin, and chemistry of mitochondrial toxins, and discuss animal models of human diseases related to abnormal mitochondrial function. The emphasis on 3-NP and its ability to replicate the cellular, anatomical, and behavioral alterations seen in Huntington's disease demonstrate that mitochondrial inhibitors play an important role in the etiology of central nervous system disorders. The book also discusses recent therapeutic modalities aimed at rescuing the central nervous system from abnormal mitochondrial functioning. With its timely, in-depth review, Mitochondrial Inhibitors and Neurodegenerative Disorders offers today's advanced investigators powerful insights into how mitochondrial toxins precipitate and exacerbate neurodegenerative disorders, and details important new treatment strategies that can halt or reverse disease progression.

Detalles del libro - Mitochondrial Inhibitors and Neurodegenerative Disorders


EAN (ISBN-13): 9780896038059
ISBN (ISBN-10): 089603805X
Tapa dura
Tapa blanda
Año de publicación: 1999
Editorial: Humana
336 Páginas
Peso: 0,728 kg
Idioma: eng/Englisch

Libro en la base de datos desde 2008-10-12T03:16:02-05:00 (Mexico City)
Página de detalles modificada por última vez el 2023-09-07T01:18:33-06:00 (Mexico City)
ISBN/EAN: 089603805X

ISBN - escritura alterna:
0-89603-805-X, 978-0-89603-805-9
Mode alterno de escritura y términos de búsqueda relacionados:
Autor del libro: sanberg, cesario
Título del libro: mitochondria, mitochondrial mitochondrial


Datos del la editorial

Autor: Paul R. Sanberg
Título: Contemporary Neuroscience; Mitochondrial Inhibitors and Neurodegenerative Disorders
Editorial: Humana; Humana Press
314 Páginas
Año de publicación: 1999-10-01
Totowa; NJ; US
Idioma: Inglés
164,99 € (DE)

BB; Hardcover, Softcover / Medizin/Nichtklinische Fächer; Neurowissenschaften; Verstehen; Nervous System; Parkinson; brain; central nervous system; chemistry; death; dopamine; hypoxia; metabolism; mitochondria; neurochemistry; neurodegenerative disorders; protein; Neuroscience; BC

I. Mitochondrial Toxins: Symptomatology, Origin, and Chemistry.- 1 • Clinical Manifestations and Mechanisms of Action of Environmental Mitochondrial Toxins.- 2 • History of 3-Nitropropionic Acid: Occurrence and Role in Human and Animal Disease.- 3 • The Neurochemistry of 3-Nitropropionic Acid.- II. Mitochondrial Dysfunctions: Models of Neurodegeneration and Mechanisms of Action.- 4 • In Vitro Studies of 3-Nitropropionic Acid.- 5 • Cognitive and Motor Deficits Produced by Acute and Chronic Administration of 3-Nitropropionic Acid in Rats.- 6 • Comparative Study on 3-Nitropropionic Acid Neurotoxicity.- 7 • Mechanisms of 3-Nitropropionic Acid Neurotoxicity.- 8 • Gender-Related Difference of the Effect of 3-Nitropropionic Acid on Striatal Artery.- 9 • Variable Susceptibility to Neurotoxicity of Systemic 3-Nitropropionic Acid.- 10 • The 3-Nitropropionic Acid Model of Huntington’s Disease: Do Alterations in the Expression of Metabolic mRNAs Predict the Development of Striatal Pathology?.- 11 • Mechanisms of Action of 3-Nitropropionic Acid: Dopamine Overflow and Vulnerability of the Lateral Striatal Artery.- 12 • Mitochondrial Inhibition and Neuronal Death in Huntington’s Disease.- 13 • Effects of Brain Mitochondrial Metabolism, Aging, and Caloric Restriction on Membrance Lipids and Proteins: An Electron Paramagnetic Resonance Investigation.- 14 • Malonate: Profile and Mechanisms of Striatal Toxicity.- 15 • Malonic Acid and the Chronic Administration Model of Excitotoxicity.- 16 • Sodium Azide-Induced Neurotoxicity.- III. Treatment Interventions for Mitochondrial-Induced Neurotoxicity.- 17 • Neuroprotective Strategies Against Cellular Hypoxia.- 18 • Neuroprotective Effect of Perinatal Hypoxia Against 3-Nitropropionic Acid Neurotoxicity.-19 • Neural Transplantation and Huntington’s Disease: What Can We Learn from the 3-Nitropropionic Acid Model?.- 20 • Neuroprotective Strategies in Parkinson’s Disease and Huntington’s Chorea: MPTP- and 3-NPA-Induced Neurodegeneration as Models.

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