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Enhancement of solubility of Mebendazole by SEDDS | Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis | Naveen Patel (u. a.) | Buch - Patel, Naveen
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Patel, Naveen:

Enhancement of solubility of Mebendazole by SEDDS | Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis | Naveen Patel (u. a.) | Buch - Pasta blanda

2012, ISBN: 9783659116339

[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], The aim of the present work was to prepare Self emulsifying drug delivery system (SEDDS) of a lipophilic drug, Mebendazole for in… Más…

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Enhancement of solubility of Mebendazole by SEDDS / Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis / Naveen Patel (u. a.) / Buch - Patel, Naveen
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Patel, Naveen:

Enhancement of solubility of Mebendazole by SEDDS / Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis / Naveen Patel (u. a.) / Buch - Pasta blanda

2012, ISBN: 9783659116339

[ED: Taschenbuch], [PU: LAP Lambert Academic Publishing], The aim of the present work was to prepare Self emulsifying drug delivery system (SEDDS) of a lipophilic drug, Mebendazole for in… Más…

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Enhancement of solubility of Mebendazole by SEDDS - Naveen Patel|Aparna Lanka
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Naveen Patel|Aparna Lanka:
Enhancement of solubility of Mebendazole by SEDDS - Pasta blanda

2012

ISBN: 3659116335

[EAN: 9783659116339], Neubuch, [PU: LAP LAMBERT Academic Publishing], MEDIZIN PHARMAZIE MEBENDAZOLE SELF EMULSIFYING DRUG DELIVERY TOCOPHEROL ACETATE PEG 200 LABRASOL, Dieser Artikel ist … Más…

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Enhancement of solubility of Mebendazole by SEDDS - Naveen Patel Aparna Lanka
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Naveen Patel Aparna Lanka:
Enhancement of solubility of Mebendazole by SEDDS - encuadernado, tapa blanda

2012, ISBN: 9783659116339

[ED: Kartoniert / Broschiert], [PU: LAP LAMBERT Academic Publishing], Dieser Artikel ist ein Print on Demand Artikel und wird nach Ihrer Bestellung fuer Sie gedruckt. Autor/Autorin: Patel… Más…

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Lanka, Aparna,Patel, Naveen:
Enhancement of solubility of Mebendazole by SEDDS: Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis - Pasta blanda

2012, ISBN: 9783659116339

LAP LAMBERT Academic Publishing, 2012-06-23. Paperback. Good. 0.7480 in x 8.4252 in x 5.8661 in., LAP LAMBERT Academic Publishing, 2012-06-23, 2.5

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Detalles del libro
Enhancement of solubility of Mebendazole by SEDDS: Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis
Autor:
Título:
ISBN:

3659116335


The aim of the present work was to prepare Self emulsifying drug delivery system (SEDDS) of a lipophilic drug, Mebendazole for increasing its solubility. Various oils, surfactants and co-surfactants were screened for their suitability in the formulation of SEDDS. Based on the initial screening, Omix of Tocopherol acetate and Peceol in the ratio 6:4 and surfactant, Labrasol and co-surfactant, PEG 200 were found to be satisfactory. Five formulations were selected from pseudoternary phase diagrams and were evaluated for parameters like drug content, percentage transmittance, dilution potential, centrifugation test, in-vitro release study, emulsification time and dispersibility, emulsion droplet size, zeta potential, polydispersibility index and ex-vivo permeation studies. All the formulations exhibited a rapid emulsification rate and a good polydispersibity index. The size of the droplets as determined by zeta sizer was found to be below 300 nm. The percentage drug release from the formulations was improved compared to that of pure drug. Thus, the formulated SEDDS helped in improving the solubility and dissolution of the drug, thereby increasing its therapeutic effectiveness.

Detalles del libro - Enhancement of solubility of Mebendazole by SEDDS: Self Emulsifying Drug Delivery System of Mebendazole with improved solubility, effective against lymphatic filariasis


EAN (ISBN-13): 9783659116339
ISBN (ISBN-10): 3659116335
Tapa dura
Tapa blanda
Año de publicación: 2012
Editorial: LAP LAMBERT Academic Publishing

Libro en la base de datos desde 2008-12-03T04:42:46-06:00 (Mexico City)
Página de detalles modificada por última vez el 2023-11-08T14:02:57-06:00 (Mexico City)
ISBN/EAN: 3659116335

ISBN - escritura alterna:
3-659-11633-5, 978-3-659-11633-9
Mode alterno de escritura y términos de búsqueda relacionados:
Autor del libro: patel, lanka
Título del libro: solubilities, enhancement, solubility

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